An in vitro study of the effectiveness of carbon dioxide flushing of arterial line filters.
نویسندگان
چکیده
Gaseous microemboli (GMEs) have been connected to neurologic impairment and other ischemic complications after surgery. The components of the extracorporeal circuit (ECC) have a large influence on GME production. This in vitro study investigates the use of carbon dioxide flushing of the 38-microm Medtronic Affinity CB351 and 38-microm Medtronic Affinity 351 arterial line filters (ALFs) to decrease GMEs and time for air to clear the ALE An adult circuit was implemented with a silicone oxygenator for vacuum-assisted gas removal and to reduce air before ALE The 48 filters were separated into four equal groups: flushed coated and non-coated and non-flushed coated and non-coated. Carbon dioxide flushing was performed at 6 L/min for 3 minutes. ALFs were retrograde primed at 200 mL/min. An Emboli Detection and Classification Quantifier (EDAC) was used to gather data. The average total emboli and time to clear (seconds) for flush coated were 20.25 +/- 16.78 and 142.17 +/- 174.80 seconds, respectively, flushed non-coated were 30.5 +/- 34.65 and 124.17 +/- 131.40 seconds, non-flushed coated were 162.08 +/- 79.90 and 390.42 +/- 84.36 seconds, and non-flushed non-coated were 163.67 +/- 212.67 and 305.92 +/- 179.36 seconds. Flushed filters had an average total emboli count of 25.375 +/- 27.14 and an average time to clear of 13.167 +/- 151.51 seconds. Non-flushed filters had an average total emboli count of 162.875 +/- 157.11 and an average time to clear of 348.167 +/- 143.70 seconds. Coated and non-coated filters for total emboli and time to clear had p values of .86 and .24, respectively. Flushed and non-flushed filters had total emboli and time to clear p values of < .001 and < .001, respectively. No significant difference was found between coated and non-coated filters involving total embolic count and time to clear. A significant difference was found in total embolic count and time to clear between flushed and non-flushed filters. This study shows that fewer emboli and faster embolic clearance time correlate with carbon dioxide flushing of the ALE.
منابع مشابه
مقایسه تاثیر روش شستشوی مداوم و متناوب بر حفظ باز بودن کاتتر شریانی در بیماران پس از عمل جراحی بای پس عروق کرونر
Background and purpose: Hemodynamic monitoring is necessary after coronary artery bypass grafting (CABG). For this purpose, the arterial line should be rinsed to prevent obstruction. There is no consensus on flushing methods. This study aimed to compare the effect of continuous and intermittent flushing on maintaining patency of the arterial line in patients after CABG. Materials and methods...
متن کاملEnd-tidal Carbon Dioxide Measurements in Unintentional Non-Fire-Related Carbon Monoxide Poisoning
Background: Poisoning with carbon monoxide occurs occasionally worldwide, and the gold diagnostic standard is to measure carboxyhemoglobin level in the blood. This study investigated the correlation between carboxyhemoglobin and the end-tidal carbon dioxide levels in 50 patients with carbon monoxide poisoning. Methods: We recruited 50 volunteer patients who had been admitted to the Emergency S...
متن کاملInvestigating the Relationship Between End Tidal Carbon Dioxide and Arterial Carbon Dioxide Pressure in Patients With Respiratory Distress Referred to the Emergency Room of Hazrat Rasool Akram Hospital
Background: Measuring End-Tidal Carbon Dioxide (ETCO-2) can be a non-invasive, fast, and reliable method to predict partial pressure of carbon dioxide (PaCO2) in patients with respiratory distress. This method, which can be a suitable substitute to measure PaCO2, is being used in many emergency rooms and operating rooms in developed countries, but its exact relationship with PaCO2 has not been ...
متن کاملStandardization and Validation of Non-invasive Monitoring of End Tidal Carbon Dioxide in Neonates via Nasal Cannula: An Observational Study
Background: Carbon dioxide (CO2) is a by-product of cellular metabolism, which could be considered as a reflection of metabolism, circulation, and ventilation. Arterial blood gas analysis (ABG) is the gold standard of monitoring for CO2. However, is an expensive method leading to blood loss and iatrogenic anemia. In addition, each sample is only a...
متن کاملGaseous Emboli Removal Efficiency in Arterial Screen Filters: A Comparative Study
____________ _ Seven commercially available arterial filters were evaluated for their effectiveness in removing gaseous emboli produced by various sources. All filters were of the screen type and ranged from 2040 micron pore size. The first phase of the study consisted of an appraisal of carbon dioxide flushing to facilitate priming. Two filters of each type were used. The first filter was prim...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The journal of extra-corporeal technology
دوره 41 3 شماره
صفحات -
تاریخ انتشار 2009